TABLE 5.

Multivariate Cox Model Analysis Controlling for Major Prognostic Variables

Variable	Overall Survival P HR (95% CI)	Disease-free Survival P HR (95% CI)	Disease-specific Survival P HR (95% CI)
Smoking	P = 0.038	P = 0.063	P = 0.36
Ever vs. never	3.7 (1.07-12.82)	2.8 (0.94-8.32)	2.7 (0.32-23.03)
T-stage	P = 0.021	P = 0.064	P = 0.029
T3/T4 vs. T1/T2	2.74 (1.16-6.45)	2.2 (0.95-4.98)	4.4 (1.15-16.38)
Treatment	P = 0.11	P = 0.05	P = 0.05
Surgery/postoperative radiation vs. definitive	0.5 (0.2-1.17)	0.43 (0.19-0.99)	0.29 (0.09-1.01)
N-stage	P = 0.65	P = 0.62	P = 0.23
N2C/N3 vs. N0-N2B	1.24 (0.48-3.19)	1.3 (0.5-3.19)	2.2 (0.6-8.21)
QuHbIC	P = 0.081	P = 0.013	P = 0.003
Positive vs. negative	2.08 (0.91-4.75)	2.65 (1.22-5.75)	6.47 (1.87-22.35)

CI indicates confidence interval; HR, hazard ratio.

P-values in bold are statistically significant, i.e., < 0.05.