The effect of nicks on the quantity of NotI-digested
sub-chromosomal fragments. Stationary cultures of recBC(Ts) and
recBC(Ts) uvrA mutants were exposed to a
variety of UV doses, and plugs were made after 10 min incubation in spent
culture medium. One set of plugs was digested with NotI and
electrophoressed, together with non-NotI digested plugs, at 6
V/cm for 20 H and 3 V/cm for 70 H.
(A) Quantification of the amount of signal, presented as %
of the total signal, in 1 Mbp NotI fragment after
electrophoresis at 6 V/cm for 20 H.
(B) The radiogram of the gel from which the data in (A) are
derived.
(C) Qauntification of the amount of signal, presented as %
of the total signal, in the compression zone after electrophoresis at 3 V/cm for
70 H.
(D) The radiogram of the gel from which the data in (C) are
derived.