Skip to main content
. Author manuscript; available in PMC: 2013 Dec 26.
Published in final edited form as: J Am Chem Soc. 2012 Dec 13;134(51):10.1021/ja310585e. doi: 10.1021/ja310585e

Figure 4.

Figure 4

Extending the dynamic range with allosteric control. We have extended the useful dynamic range of our model cocaine sensor to 50,000-fold using a single aptamer sequence (the parent sequence) and a mixture of two allosteric inhibitors of different length (10mer and 14mer). Here concentration of the aptamer was 125 nM and the two inhibitors (inhib_10 and inhib_14) were used at 44 nM and 56 nM respectively.