Table 1.
Head twitch response (HTR) induced by substituted phenethylamines.
Compound code | ED50 (μmol/kg) | Relative potency | ED50 (mg/kg) | 95% C.L. (mg/kg) | Max HTR counts (mean±SEM)1 | Dose (mg/kg)2 |
---|---|---|---|---|---|---|
2C-I | 2.42 | 1.0 | 0.83 | 0.50–1.38 | 93.8±7.4 | 3 |
25I-NBOMe | 0.17 | 14.2 | 0.078 | 0.054–0.11 | 102.6±8.7 | 1 |
25I-NBMD | 2.36 | 1.0 | 1.13 | 0.68–1.86 | 80.2±9.5 | 10 |
Counts per 30 min.
Dose producing the maximal response.