Table 1.

Experimental design

Experiment	Treatment	Interval between treatment and testing	Test duration	Animals	Design
DOI dose-response	Vehicle or DOI (0.25, 0.5, 1.0mg/kg)	0 min	10 min	n = 13	4-way semi-randomized crossover with 1week between tests
(+)- Amphetamine dose-response	Vehicle or (+)-amphetamine (2.5, 5.0 mg/kg)	20 min	10 min	n = 5–7 (18 total)	Between-subjects
SKF38393	Vehicle or 10 mg/kg SKF38393	20 min	10 min	n = 5 (10 total)	Between-subjects
LSD dose-response	Vehicle or LSD (50, 100, 200, 400 μg/kg)	0 min	30 min	n = 5 (25 total)	Between-subjects
Lisuride dose-response	Vehicle or lisuride (0.8, 1.6, 3.2 mg/kg)	0 min	30 min	n = 5 (20 total)	Between-subjects