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. 2013 Dec 17;8(12):e84075. doi: 10.1371/journal.pone.0084075

Figure 1. Bitter melon ameliorated fat deposition and insulin resistance in mice fed with HFD.

Figure 1

Five-week-old male C57BL/6 mice were grouped and fed on the diets indicated in Table 1. (A) Body weight gain of the mice. (B) The weights of epididymal adipose tissues (EAT), subcutaneous adipose tissues (SAT) and brown adipose tissues (BAT) of the mice. (C) Insulin tolerance and (D) glucose tolerance assays were performed at 17-week-old in the mice. The insulin (E) and leptin (F) concentrations in serum of mice. (G) The energy intake per 20g bodyweight of mice during 12-week treatment. Statistical difference between groups is shown using a nonparametric Mann-Whitney test. n=8 per group. *P<0.05, **P<0.01. All data are means ± SEM.