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. 2013 Dec 17;8(12):e84492. doi: 10.1371/journal.pone.0084492

Figure 7. Longitudinal examination of whole brain and hippocampal growth from pre and post enrichment (or non-enrichment) MRI scans.

Figure 7

(A) Control animals did not differ at the initial scan, but at P150 there was a significant difference between those housed in enriched vs. non-enriched settings (time*enrichment interaction; p=0.022). (B) The same was true for MAM animals. There was no enrichment effect in the hippocampal volumes (p=0.624). (C) For the hippocampus but not the whole brain, there was an effect of MAM on growth longitudinally (time*MAM interaction; p=0.009) as shown by a greater volume change over time in the MAM hippocampus compared to the controls. Error bars represent standard error.