Figure 1. ChIRP (Chromatin Isolation by RNA purification) analysis shows that Fendrr interacts with target promoters in embryonic stem cells differentiated in vitro. Fourteen biotinylated oligonucleotides tiling the Fendrr transcript were combined in even and odd numbered pools. (A) Each oligo-pool specifically precipitated the Fendrr transcript. (B) At least one pool of tiling oligos co-precipitated the target promoters of Foxf1 and Pitx2, but not the control promoters of Dll1, Tcf15, or Irx3.