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. 2013 Aug 22;10(10):1579–1585. doi: 10.4161/rna.26165

graphic file with name rna-10-1579-g2.jpg

Figure 2.Fendrr anchors PRC2 to specific target sites. Schematic drawing illustrating binding of the Fendrr/PRC2 complex through a 40-nucleotide stretch (red) to specific recognition sequences in target promoters, e.g., that of Foxf1 and Pitx2, thus increasing PRC2 occupancy and H3K27 trimethylation at these sites.