Table 2. Editing levels in filamin A pre-mRNA during post-natal development.
| Organ | P0 | P20 | P120 |
|---|---|---|---|
|
lung |
48.6 (961k) |
57.8 (331k) |
66.5 (176k) |
|
aortic arch |
53.3 (550k) |
nd |
54.9 (Sanger) |
|
heart |
29.6 (595k) |
34.7 (16k) |
26.9 (134k) |
|
muscle |
28.9 (213k) |
26.6 (13k) |
33.7 (1k) |
|
cartilage |
18.5 (420k) |
nd |
29.0 (27k) |
|
bone |
22.6 (102k) |
18.7 (354k) |
30.5 (95k) |
|
skin |
23.1 (142k) |
16.3 (140k) |
26.3 (9k) |
|
stomach |
30.7 (163k) |
32.2 (135k) |
93.4 (146k) |
|
small intestine |
nd |
2.3 (127k) |
15.9 (74k) |
|
large intestine |
nd |
11.5 (24k) |
84.5 (138k) |
|
pancreas |
9.7 (414k) |
28.6 (558k) |
35.6 (166k) |
|
spleen |
11.7 (488k) |
11.6 (48k) |
13.9 (19k) |
|
Liver |
13.3 (55k) |
14.9 (2k) |
24.0 (0.5k) |
|
kidney |
8.8 (76k) |
11.5 (300k) |
22.8 (6k) |
|
bladder |
45.6 (392k) |
nd |
54.2 (114k) |
|
brown fat |
7.1 (228k) |
nd |
nd |
|
eyes |
11.1 (431k) |
nd |
51.3 (355k) |
|
olfactory bulb |
19.8 (288k) |
6.3 (29k) |
35.3 (28k) |
|
cortex |
10.3 (143k) |
9.0 (10k) |
38.0 (127k) |
|
hippocampus |
nd |
32.6 (230k) |
38.8 (41k) |
|
thalamus/hypot. |
nd |
33.4 (119k) |
32.0 (12k) |
|
cerebellum |
33.7 (5k) |
24.5 (28k) |
38.0 (111k) |
| spinal cord | nd | 21.2 (6k) | 27.0 (5k) |
cDNAs prepared from the organs indicated were amplified, bar-coded, and sequenced on an Illumina GAII platform. Editing levels were calculated for each tissue and are listed in %. Nd, not determined. Read depth is indicated in 1000 (k) in brackets.