Table 3. Editing levels at E 15.5 in ADAR2−/− mice.
| Region | Editing in % |
|---|---|
|
head |
0.3 (614k) |
|
brain |
0.2 (305k) |
|
thorax+abdomen |
1.3 (243k) |
| abdomen | 0.2 (675k) |
E 15.5 embryos were dissected into the regions indicated and cDNAs of the FLNA mRNA were amplified, bar coded, and sequenced on an Illumina GA II platform. Editing levels are indicated in %. As background basecall errors lay around 0.3%, significant editing levels can only be identified in thorax+abdomen. Read depth is indicated in 1000 (k) in brackets.