Figure 7.

Mitochondrial fragmentation in M17 cells. A, Representative images of mitochondria in α-syn-expressing cells labeled with pDsRed2-Mito. Insets, Enlargements of the indicated regions (small boxes). B, Quantitation of fragmentation of the cells in A, measured as the percentage of all cells that contained predominantly fragmented (darker shading) versus tubular (lighter shading) mitochondria. Numbers within the boxes denote the average length (±SE) of the mitochondria in micrometers; n = number of mitochondria measured. *Significant difference versus EV (p < 0.05).