Figure 8.

Both green-sensitive and blue-sensitive cones are functional in the absence of Gβ3. A, B, Ten hertz flicker ERG responses elicited by γ = 365 (A) and 513 nm (B) flashes delivering ∼140,000 and 240,000 photons/mm² at the cornea on a background illumination of 30 scot cd m⁻² in WT and KO (Gnb3^−/−) mice. C, Response amplitude versus intensity functions (plotted on logarithmic coordinates) for cone-driven flicker responses in a WT and Gnb3^−/− mice. Lines of unity slope, that represent linear relationships between peak amplitude and intensity, were fitted to the four lowest points. These values for the null mouse were 0.28 and 0.099 respectively. D, Sensitivity of the 10 Hz flicker responses to stimulation of 365 and 513 nm for WT (3.0 ± 1.7 and 1.01 ± 0.56 nV photon⁻¹ μm², n = 5) and Gnb3^−/− (0.33 ± 0.18 and 0.16 ± 0.09 nV photon⁻¹ μm², n = 4) mice. E, The ratio of 365 sensitivity to visible light sensitivity from data in C: WT (3.36 ± 1.07, n = 5) and Gnb3^−/− (2.32 ± 0.92, n = 4).