Figure 5.

Overview of methanol utilization and related metabolic processes in H. polymorpha. Methanol- and glucose-induced genes are shown in red and blue, respectively. Enzyme abbreviations: AOX, alcohol oxidase; CAT, catalase; DAS, dihydroxyacetone synthase; DAK, dihydroxyacetone kinase; FLD, formaldehyde dehydrogenase; FGH, S-formyl glutathione hydrolase; FDH, formate dehydrogenase; GLK, glucokinase; PGI, glucose-6-phosphate isomerase; PFK, phosphofructokinase; FBP, fructose-1,6-bisphosphatase; FBA, fructose-bisphosphate aldolase; TPI, triosephosphate isomerase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGAM, phosphoglycerate mutase; ENO, enolase; PYK, pyruvate kinase; PYC, pyruvate carboxylase; PEPCK, phosphoenolpyruvate carboxykinase; TKT, transketolase; TAL, transaldolase.