Table 1.
Development of BCB+ immature oocyte cultured in the maturation medium supplemented with different concentrations of melatonin
| Group | No. oocyte | MI | Cumulus expansion | MII |
|---|---|---|---|---|
| Control | 204 | 64(31.46 ± 3.41) a,b | 187(91.62 ± 1.25)e | 136(66.69 ± 3.26) f,g,h |
| DMSO | 203 | 83(40.76 ± 5.25) | 164(81.04 ± 2.35) | 120(59.24 ± 5.25) |
| Melatonin 10-3M | 198 | 93 (46.56 ± 23.27) | 131(66.24 ± 15.46) | 105(52.73 ± 20.7) |
| Melatonin 10-6M | 188 | 44(23.63 ± 12.29) c,d | 163(87.1 ± 7.22) | 144(76.37 ± 12.29) f,i,k |
| Melatonin 10-9M | 201 | 109(54.13 ± 16.98 )a,c | 161(80.17 ± 14.29) | 92(45.87 ± 16.98)g,i |
| Melatonin 10-12M | 206 | 121(58.90 ± 16.55) b,d | 130(63.15 ± 15.41)e | 85(41.1 ± 16.55) h,k |
Within the same column, values with same letters were significantly different (p <0.05).