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. Author manuscript; available in PMC: 2013 Dec 18.
Published in final edited form as: Virology. 2007 Mar 21;364(1):10.1016/j.virol.2007.02.007. doi: 10.1016/j.virol.2007.02.007

Table 1.

Epitope specificity, TCRβ usage and epitope substitutions that illustrate differences in fine specificity for SV40 T ag-specific CTL clones used in this study

CTL clonea Restriction SV 40 T ag epitope specificity TCRβb Fine specificityc
Y-1 H-2Db I 7 S206T
A207G
N209T
K-11 H-2Db I 10 A212G/C
Q213H
K-19 H-2Db II/III 10 NAd
Y-5 H-2Db V 7
Q489A
D495A
H-1 H-2Db V 9
a

References for the derivation and characterization of each of the CTL clones are provided in the text.

b

For additional information, see Mylin, et al. 2000.

c

Substituted epitope sequences which are differentially recognized by these pairs of CTL clones. For further information regarding the fine specificities of the epitope I-specific CTL clones Y-1 and K-11, see Lippolis, et al. 1995 and Tevethia, et al. 1998. The epitope V-specific CTL clones Y-5 and H-1 displayed differential recognition of alanine substituted synthetic peptides (Mylin and Tevehia, unpublished).

d

Not applicable.