Fig. 28.

The structure of s-COMT. A cartoon of the s-COMT structure coloured blue at the N-terminus through to red at the C-terminus. The secondary structure elements are labelled as in Fig. 27: H – helix and S – sheet. SAM and DNC are shown with purple carbons. The yellow sphere is a magnesium ion. Based on the 3BWM structure [136]. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)