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PET time-activity curves in selected brain regions of rhesus monkeys administered [18F]11 at: baseline (panel A); after preblock of mGluR1 with 17 (panel B); in an experiment in which 17 (3 mg/kg, i.v.) was administered at 30 min (panel C); and in an experiment in which the selective mGluR5 ligand 18 (5 mg/kg, i.v.) was administered at 30 min (Panel D).
