Fig. 4.
Whole-body planar imaging of cardiac cell death using 99mTc-Duramycin prepared from a single-step kit formulation (Tricine/TPPTS 10:1). There is prominent focal uptake of 99mTc-Duramycin in cardiac tissues damaged by ischemia and reperfusion (arrow), whereas no such binding occurs in sham operated animal (left). The radiotracer clears via the renal/urinary system with low systemic background. Kidneys and the bladder are marked by “K” and “B”, respectively.