Table 2. The Comparison of Liver Fat Content, Anthropometric Measurements, and Laboratory Parameters Between the Treatment Groups During the Study a.
| Lifestyle modification plus H. pylori eradication | Lifestyle modification | P value | |
|---|---|---|---|
| Liver fat content, mean ± SD | |||
| Baseline | 12.5 ± 7.2 | 12.2 ± 7.9 | 0.8 |
| Eight weeks | 10.7 ± 6.1 | 10.2 ± 6.9 | 0.7 |
| Twenty four weeks | 8.9 ± 5.1 | 8.6 ± 6.1 | 0.7 |
| Waist Circumference, mean ± SD, cm | |||
| Baseline | 101.2 ± 2.8 | 100.7 ± 2.6 | 0.3 |
| Eight weeks | 101.1 ± 2.7 | 100. 6 ± 2.5 | 0.3 |
| Twenty four weeks | 98.1 ± 1.7 | 98.2 ± 1.7 | 0.8 |
| Weight, kg | |||
| Baseline | 87.6 ± 12.1 | 88.5 ± 8.5 | 0.6 |
| Eight weeks | 86.8 ± 11.5 | 87.6 ± 8.7 | 0.7 |
| Twenty four weeks | 79.4 ± 9.3 | 80.1 ± 6.8 | 0.6 |
| Body mass index, kg/m 2 | |||
| Baseline | 31.2 ± 4.1 | 30.4 ± 4.2 | 0.3 |
| Eight weeks | 30.9± 3.9 | 30.1 ± 4.1 | 0.2 |
| Twenty four weeks | 28.3 ± 3.2 | 27.5 ± 3.5 | 0.2 |
| Aspartate aminotransferase, U/L | |||
| Baseline | 46.5 ± 19.9 | 46.4 ± 21.2 | 0.9 |
| Eight weeks | 38.3 ± 15.2 | 39.2 ± 18.7 | 0.8 |
| Twenty four weeks | 32.4 ± 13.0 | 33.4 ± 15.4 | 0.7 |
| Alanine aminotransferase, U/L | |||
| Baseline | 68.6 ± 26.1 | 73.5 ± 30.8 | 0.4 |
| Eight weeks | 53.7 ± 30.5 | 53.3 ± 33.3 | 0.9 |
| Twenty four weeks | 41.9 ± 22.1 | 41.3 ± 25.6 | 0.9 |
| Alkaline phosphatase, U/L | |||
| Baseline | 182.3± 58.5 | 191.8 ± 50.9 | 0.3 |
| Eight weeks | 172.8 ± 51.6 | 187.4 ± 48.5 | 0.1 |
| Twenty four weeks | 162.7 ± 41 | 176.5 ± 41.4 | 0.1 |
| Triglyceride, mg/dL | |||
| Baseline | 174.8 ± 103.2 | 155.8 ± 83.4 | 0.3 |
| Eight weeks | 137.5 ± 79.0 | 124.4 ± 52.2 | 0.3 |
| Twenty four weeks | 119.9 ± 48.1 | 115.8 ± 40.3 | 0.6 |
| Cholesterol, mg/dL | |||
| Baseline | 180.8 ± 31.9 | 183.3 ± 40.3 | 0.7 |
| Eight weeks | 171.5 ±26.9 | 173.3 ± 31.7 | 0.7 |
| Twenty four weeks | 167.2 ± 20.8 | 168.0 ± 23.1 | 0.8 |
| Low density lipoprotein, mg/dL | |||
| Baseline | 101.8 ± 25.7 | 108.7 ± 37.1 | 0.2 |
| Eight weeks | 97.1 ± 23.3 | 102.4 ± 29.7 | 0.3 |
| Twenty four weeks | 91.5 ± 19.3 | 93.8 ± 21.0 | 0.5 |
| High density lipoprotein, mg/dL | |||
| Baseline | 44.5 ± 5.7 | 43.1 ± 5.8 | 0.2 |
| Eight weeks | 46.9 ± 5.5 | 46.0 ± 7.1 | 0.5 |
| Twenty four weeks | 51.7 ± 7.0 | 51.0 ± 8.1 | 0.6 |
| Fasting plasma glucose, mmol/L | |||
| Baseline | 5.9 ± 0.8 | 5.8 ± 0.8 | 0.5 |
| Eight weeks | 5.5 ± 0.5 | 5.5 ± 0.6 | 0.6 |
| Twenty four weeks | 5.2 ± 0.7 | 5.3 ± 0.6 | 0.5 |
| HOMA-IR b | |||
| Baseline | 5.2 ± 1.9 | 5.0 ± 2.1 | 0.6 |
| Eight weeks | 4.3 ± 1.5 | 4.1 ± 1.7 | 0.6 |
| Twenty four weeks | 3.6 ± 1.4 | 3.5 ± 1.6 | 0.7 |
b Abbreviation: HOMA-IR, Homeostasis model assessment-insulin resistance
aData presented as mean ± standard deviation