Table 3. Neutrophil elastase (NE) peptides identified by epitope mapping.
| Donor ID | NE | Peptide sequence | HLA restriction | AA no. | HLA-A | HLA-B | HLA-Cw | HLA-DRB | HLA-DQB |
|---|---|---|---|---|---|---|---|---|---|
| 1 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 0201 | 15/39 | 03/12 | 0403/0701 | 0202/03 |
| 2 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 0201/01 | 08/44 | 05/07 | 0301/0401 | 0201/0301 |
| 3 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 0201/26 | 27/39 | 07/12 | 1501/1601 | 0502/0602 |
| No. 9 | GRRARPHAWPFMVSL | Class I | 33–47 | ||||||
| No. 16 | APNFVMSAAHCVANV | HLA-DR | 61–75 | ||||||
| 4 | No. 5 | PALLLGGTALASEIV | Class I | 17–31 | |||||
| 5 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 01/0201 | 08/44 | 05/07 | 0301/0401 | 02/0301 |
| No. 8 | EIVGGRRARPHAWPF | Class I | 29–43 | ||||||
| 6 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 0201 | 15/57 | 01/06 | 07/1501 | 0303/0602 |
| No. 30 | DIVILQLNGSATINA | HLA-DR | 117–131 | ||||||
| 7 | No. 2 | RRLACLFLACVLPAL | Class I | 5–19 | 0201 | 44 | 04/05 | 03/0401 | 0201/03 |
| No. 5 | PALLLGGTALASEIV | Class I | 17–31 | ||||||
| 9 | No. 59 | APVAQFVNWIDSIIQ | Class I | 223–247 | 3/11 | 07/56 | 01/07 | 0101/0701 | 02/0501 |
| No. 9-11 | GRRARPHAWPFMVSLQLRGGHFC | HLA-DR | 33–51 |
Abbreviation: AA, amino acids, HLA, human leukocyte antigen.