. Author manuscript; available in PMC: 2013 Dec 18.

Published in final edited form as: JAMA Intern Med. 2013 Jun 24;173(12):10.1001/jamainternmed.2013.714. doi: 10.1001/jamainternmed.2013.714

Table 3.

Adjusted odds or rate ratios for outcomes for SSRI treatment in the overall sample, and in selected patient subgroups

Patient group	Entire sample	Patients on SSRI or no antidepressant	Among patients on any antidepressants	Among patients on SSRI only or SNRI only	Among patients with depression	Among patients with depression
Sample size	n=530,416	n=475,456	n=117,544	n=82,134	n=60,777	N=40,213
Overall n and % on SSRI	72,540 (13.7%)	62,584 (13.2%)	72,540 (61.7%)	62,584 (76.2%)	30,923 (50.9%)	25,824 (64.2%)
Comparison groups	SSRI vs. overall	SSRI vs. no other antidepressants	SSRI vs. other treatments	SSRI only vs. SNRI only	SSRI vs. other treatments	SSRI vs. no other antidepressants
	Adjusted OR/Rate Ratio (95% CI)	Adjusted OR/Rate Ratio (95% CI)	Adjusted OR/Rate Ratio (95% CI)	Adjusted OR/Rate Ratio (95% CI)	Adjusted OR/Rate Ratio (95% CI)	Adjusted OR/Rate Ratio (95% CI)
Mortality (Adjusted Odds, 95% CI)	1.20 (1.07, 1.36)	1.22 (1.07, 1.38)	1.04 (0.87, 1.25)	1.54 (1.18, 2.01)	0.86 (0.65, 1.13)	1.00 (0.72, 1.37)
Bleeding (Adjusted Odds, 95% CI)	1.09 (1.04, 1.15)	1.21 (1.17, 1.26)	1.00 (0.93, 1.08)	0.90 (0.85, 0.96)	1.10 (1.03, 1.18)	1.15 (1.01, 1.32)
Readmission 30 days (Adjusted Odds, 95% CI)	1.22 (1.18, 1.26)	1.08 (1.02, 1.14)	0.98 (0.94, 1.03)	1.00 (0.89, 1.12)	1.16 (1.04, 1.29)	1.08 (0.99, 1.17)
Ventricular arrhythmia (Adjusted Odds, 95% CI)	0.89 (0.83, 0.96)	0.87 (0.79, 0.96)	1.10 (0.95, 1.28)	1.05 (0.86, 1.29)	0.82 (0.68, 0.98)	0.98 (0.97, 0.99)
Transfusion count (Adjusted rate ratio, 95% CI)	1.10 (1.08, 1.13)	1.02 (1.01, 1.02)	0.98 (0.97, 0.99)	0.97 (0.96, 0.99)	0.99 (0.98, 1.00)	1.10 (1.08, 1.13)
Length of Stay (Adjusted rate ratio, 95% CI)	1.02 (1.02, 1.03)	1.10 (1.07, 1.12)	1.09 (1.06, 1.13)	1.00 (0.96, 1.03)	1.04 (1.01, 1.08)	0.98 (0.97, 0.99)