Table 5.
Association between FGF23 Levels and LV Volumes
Percentage Change in LV End Diastolic Volume (95% CI)* | Percentage Change LV End Systolic Volume(95% CI)* | |
---|---|---|
Doubling of FGF23 | ||
Stratified by 25(OH)D | ||
25(OH)D≥20 ng/ml | 2.0(0.1,3.8) | 2.8(0.1, 5.6) |
25(OH)D<20 ng/ml | 3.6(1.4,5.8) | 5.8(2.7, 9.0) |
| ||
Doubling of FGF23 | ||
Stratified by 1,25(OH)2D | ||
1,25(OH)2D≥26.9 pg/ml | 2.7(0.8, 4.6) | 2.9(0.2, 5.7) |
1,25(OH)2D<26.9 pg/ml | 2.7(0.7, 4.8) | 5.4(2.4, 8.5) |
The regression models for log transformed LV EDV or ESV include FGF23. In addition, the models include age, gender, African American race, BMI, eGFR, atrial fibrillation, and natural log of PTH. The percentage differences in LV EDV or ESV (with 95% CI) associated with a doubling in FGF23 are estimated as in Table 3.