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. 2013 Dec 18;8(12):e82312. doi: 10.1371/journal.pone.0082312

Figure 4. Parameters of brain homeostasis during BAL treatment of pigs with ischaemic liver failure: Brain metabolites.

Figure 4

Microdialysate samples (18 µl) were collected from catheters on each side of the brain. Fig 4 A&B show glucose levels in the brain during the course of treatment using a cell-bead BAL (4A) or an empty bead BAL control (4B). Left and right refer to left and right brain hemispheres. 30 minute microdialysates were collected; measurements made hourly. Fig 4C&D show the lactate:pyruvate ratio indicating ischaemic damage in cell-bead BAL (4C) and empty bead BAL control (4D); note that 4D shows different results on each side of the brain, perhaps indicating patchy brain ischaemia. These results are representative of the 4 pigs in which microdialysis was performed, two in Group 1 and two in Group 2.