Table 1. Effect of Lum, LumC50 and LumC-peptides on wound healing of HTCE cells.
Culture condition | Rate constant 1 Δ%/h | Rate constant 2 Δ%/h |
Basic medium (9) | 3.37±0.71 | N.A. |
Complete medium (8) | 6.12±0.85(P<0.01)a | 16.86±1.71 |
GST (9) | 3.39±0.68(P = 0.95)a | N.A. |
GST-Lum (7) | 5.37±1.17(P<0.01)a | 14.83±1.61 |
GST-LumC50 (8) | 5.35±1.21(P<0.01)a (P = 0.97)b | 14.04±1.34(P = 0.98)c |
LumC33ΔC20 (3) | 3.45±0.33(P = 0.87)a (P<0.05)b | N.A. |
LumC18ΔC5 (3) | 3.62±0.42(P = 0.59)a (P<0.05)b | N.A. |
LumC13 (5) | 4.62±0.68(P<0.01)a (P = 0.23)b | 13.5±2.13(P = 0.28)c |
LumC13C-A (5) | 5.1±0.85 (P<0.01)a (P = 0.67)b | 13.95±2.38(P = 0.59)c |
a compared to BM; b,c compared to GST-Lum. Numbers in parenthesis represent the number of experiments performed. P value <0.05 is considered significant. NA – not applicable. Statistical analysis using one way ANOVA: