Table 2. Effects of ALK5 inhibitor and shRNA on Wound Healing of HTCE cells.
| Culture condition | Rate constant 1 Δ%/h | Rate constant 2 Δ%/h |
| Basic medium (9) | 3.37±0.71 | N.A. |
| Basic medium + ALK5 inhibitor (3) | 1.82±0.15 (P<0.01)a | N.A. |
| GST (9) | 3.39±0.68(P = 0.95)a | N.A. |
| GST + ALK5 inhibitor (3) | 1.83±0.17 (P<0.01)a | N.A. |
| GST-Lum (7) | 5.37±1.17(P<0.01)a | 14.83±1.61 |
| GST-Lum+ALK5 inhibitor (3) | 1.89±0.33 (P<0.01)a P<0.01)b | N.A. |
| Complete medium (9) | 6.12±0.85(P<0.01)a | 16.86±1.71 |
| Complete medium + control RNA (3) | 5.72±0.86 | 17.28±0.45 |
| Complete medium + ALK5 shRNAi (3) | 5.09±0.83(P = 0.40)c | 16.33±1.44(P = 0.34)c |
| Basic medium + control RNA (3) | 3.45±0.63 | N.A. |
| Basic medium + ALK5 shRNAi (3) | 2.94±0.32 (P = 0.27)d | N.A. |
| GST-Lum + control RNA (3) | 5.29±0.85 | 16.1±0.93 |
| GST-Lum + ALK5 ShRNAi (3) | 2.85±0.71 (P<0.05)e | N.A. |
a compared to basic medium; b, c compared to GST-Lum; d compared to complete medium + control RNA; e compared to basic medium + control RNA; f compared to GST-Lum + control RNA. P value <0.05 is considered significant.GST – Glutathione S-transferase. Statistical analysis using one way ANOVA: