Table 2. Summary of the thin filament activated ATPase pCa curves for human β-cardiac S1 at 30°C.

TnT	Disease	pCa50	ΔpCa50	% Maximum Activity	% Minimum Activity	nH	n
WT		6.17±0.01	−	100±1%	10±1%	1.2±0.1	33
I79N	HCM	6.44±0.04*	+0.27	100±2%	7±1%	1.2±0.1	11
E163K	HCM	6.36±0.03*	+0.19	147±7% *	15±1%	1.4±0.2	11
R141W	DCM	5.96±0.02*	−0.21	93±2% *	5±1%	1.2±0.1	11
R173W	DCM	6.08±0.01*	−0.09	101±4%	6±1%	1.5±0.1	15

Mean ± SEM.

n_H is the Hill coefficient.

n, represents number of individual ATPase pCa curves.

^*, p<0.001 by Mann-Whitney Rank Sum Test.