Table 3. Analysis of patients' compliance for persistent patients (MPR - Medical Possession Ratio).

	Type	No.	Min	ASL associated with min	Max	ASL associated with max	Mean Diff.	SD	CI 95% Low. Lim.	CI 95% Upp. Lim.	p-value
Metformin	Branded	6410	0.47	Milano city	0.55	Lecco	0.03	0.01	0.02	0.04	<0.0001
A10BA02	Generic	7688	0.46	Lecco	0.58	Melegnano
Amlodipine	Branded	11435	0.75	Milano city	0.84	Melegnano	0.04	0.01	0.04	0.05	<0.0001
C08CA01	Generic	5101	0.79	Milano city	0.87	Melegnano
Simvastatin	Branded	6355	0.42	Milano city	0.48	Melegnano e Lecco	0.03	0.01	0.02	0.04	<0.0001
C10AA01	Generic	10133	0.45	Milano city	0.50	Melegnano
Sertraline	Branded	3822	0.63	Milano city	0.68	Bergamo e Melegnano	0.03	0.01	0.01	0.04	0.0003
N06AB06	Generic	3176	0.63	Lecco	0.72	Melegnano
Propafenone	Branded	805	0.62	Milano city	0.72	Melegnano	0.04	0.02	−0.01	0.08	N.S.
C01BC03	Generic	328	0.65	Lecco	0.83	Melegnano
Alendronate	Branded	1821	0.68	Lecco e Pavia	0.73	Melegnano	0.01	0.01	−0.01	0.03	N.S.
M05BA04	Generic	1605	0.69	Milano city	0.74	Bergamo

ASL: Local Healthcare Units. ASLs enrolled: Milano city; Lecco; Bergamo; Pavia; Milano2.

DDD: Defined Daily Dose.

N.S. not statistically significant.