Table 1. Candidate driver genes in deleted FMCR.
Chromosomal location | Start | End | Size (Mb) | Recurrence (%) | SDE | Genes | Candidate genes* |
---|---|---|---|---|---|---|---|
3p14.3 | 57521404 | 57652691 | 0.13 | 24.44 | 4 | 3 | |
3p14.2 | 60078018 | 61195823 | 1.12 | 31.11 | 7 | 1 | FHIT |
4q22.1 | 91340468 | 92674544 | 1.33 | 33.33 | 8 | 2 | TMSL3 |
6q26 | 162357125 | 163049854 | 0.69 | 22.22 | 7 | 1 | PARK2 |
11p15.4 | 9172449 | 9363610 | 0.19 | 22.22 | 5 | 3 | |
12q14.2 | 63277389 | 63368109 | 0.09 | 20.00 | 4 | 1 | RASSF3 |
14q13.2 | 34108596 | 34950339 | 0.84 | 28.89 | 5 | 9 | NFKBIA |
16p13.3-p13.2 | 6132536 | 7018275 | 0.89 | 24.44 | 7 | 1 | A2PB1 |
17p13.1-p12 | 10957541 | 12400968 | 1.44 | 48.89 | 5 | 3 | MAP2K4 |
20p12.1 | 14376202 | 16071135 | 1.69 | 37.78 | 10 | 1 | MACROD2 |
21q22.11 | 33554005 | 33651205 | 0.10 | 28.89 | 7 | 3 | IFNAR1, IFNAR2 |
* Candidate genes defined based on cancer-relevant functions.