Table 2. CD-acquired conformation and thermal stability of mutant telomeric oligonucleotides.

sequence	topology at 20°C	Tm (290 nm)	ΔTm
wt	hybrid	61.4 ± 0.2	-
C1	antiparallel	59.5 ± 0.2	-1.9
C1a	antiparallel/hybrid	60.7 ± 0.2	-0.7
C1b	antiparallel/hybrid	60.4 ± 0.2	-1.0
C1c	antiparallel/hybrid	61.0 ± 0.1	-0.4
C2	antiparallel/hybrid	58.2 ± 0.2	-3.2
C2a	hybrid = wt	59.4 ± 0.3	-2.0
C2b	hybrid = wt	59.9 ± 0.2	-1.5
C2c	hybrid = wt	60.1 ± 0.1	-1.3
C3	hybrid ≠ wt	63.6 ± 0.2	+2.2
C3a	hybrid = wt	62.2 ± 0.3	+0.8
C3b	hybrid ≠ wt	63.4 ± 0.1	+2.0
C3c	hybrid ≠ wt	62.5 ± 0.3	+1.1
C3d	antiparallel/hybrid	61.8 ± 0.2	+0.4
CCC1	antiparallel	60.8 ± 0.1	-0.6
CCC2	hybrid ≠ wt	59.0 ± 0.3	-2.4
CCC3	antiparallel	57.8 ± 0.2	-3.6
T3	hybrid = wt	60.5 ± 0.1	-0.9
A2T3	hybrid = wt	58.1 ± 0.1	-3.3
A1T3	hybrid = wt	47.9 ± 0.5	-13.5

T_m with standard deviation values are indicated.