Table 1. IC50 of BBR derivatives measured for pNPP hydrolysis by EYA3.
Compound | IC50 μM (95% confidence intervals) |
---|---|
BBR | 8.1 (7.4 – 9.3) a |
6OH-BBR | 21.5 (18.3 – 25.3) |
1’OH-BBR | 52.5 (33.9 – 81.5) |
5OH-BBR | 49.4 (23 – 105)) |
DMBZ | 135.2 (121.9 – 150.1) |
DIBZI | 20.5 (18.9 – 22.2) |
BZI | 8.9 (8.5 – 9.4) |
BZ | 17.5 (16.2 – 18.8) a |
1b | 9.7 (8.3 – 11.4) a |
ODAA | 3.1 (2.6 – 3.7) |
OH-ODAA | 16.4 (14.9 – 17.9) |
a indicates IC50 values reported previously [13]