Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Sep 30;5(1):31–48. doi: 10.1002/wrna.1195

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. WIREs RNA published by John Wiley & Sons, Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Domain structures of ribonuclease III (RNase III) family polypeptides. Domain key: RIII (gray), RNase III domain; dsRBD (light blue), dsRNA-binding domain; PR (orange), proline-rich domain; RS (Blue), arginine/serine-rich domain; DExD/H (blue), helicase domain; DUF (brown), DUF283 domain; PF (green), platform domain; PAZ (purple), PAZ domain; C2H2 (pink): C2H2 Zinc finger domain; PUF (yellow), Pumilio/FBF homology domain. The blue double-headed arrow between the PAZ and RIIIa domains of human and giardia Dicer indicates the dsRNA ‘measuring’ segment. The parentheses in the PUF domain of mRPN1 indicate that the identity of the domain has not been confirmed. For RNC1, the red letters ‘X’ refer to inactivating point mutations of catalytic site residues. Diagrams are not to scale.