Table 4.
Regression model testing and interactive effect of OCPs (ppb) in maternal blood and CYP17 genotype on the outcome as preterm birth in cases
| Maternal Blood | ||
|---|---|---|
|
|
||
| Bb | p value | |
| α-HCH (≥ 50th vs. < 50th) | -0.546 | 0.640 |
| CYP17 (Heterogygous vs. other) | 0.381 | 0.695 |
| Interaction terma | -1.207 | 0.231 |
| β-HCH (≥ 50th vs. < 50th | 0.351 | 0.770 |
| CYP17 (Heterogygous vs. other) | 0.086 | 0.919 |
| Interaction terma | -2.11 | 0.019 |
| γ-HCH (≥ 50th vs. < 50th) | 1.123 | 0.298 |
| CYP17 (Heterogygous vs. other) | -0.079 | 0.922 |
| Interaction terma | -2.40 | 0.007* |
| p,p’-DDT (≥ 50th vs. < 50th) | -0.860 | 0.337 |
| CYP17 (Heterogygous vs. other) | 0.528 | 0.506 |
| Interaction terma | -0.278 | 0.797 |
| p,p’-DDE (≥ 50th vs. < 50th) | 0.146 | 0.894 |
| CYP17 (Heterogygous vs. other) | 0.369 | 0.642 |
| Interaction terma | -1.031 | 0.251 |
| Endosulfan (≥ 50th vs. < 50th) | -0.494 | 0.658 |
| CYP17 (Heterogygous vs. other) | 0.556 | 0.426 |
| Interaction terma | -0.198 | 0.833 |
| p,p’-DDD (≥ 50th vs. < 50th) | -0.396 | 0.612 |
| CYP17 (Heterogygous vs. other) | 0.013 | 0.982 |
| Interaction terma | -0.077 | 0.904 |
a
After adjustment of factors like age, period of gestation, diet, socioeconomic status, source of water supply, living style, parity.
b
B is un-standardized regression coefficient and this represents the mean period of gestation.
*
p < 0.005 is considered as significant (after Bonferroni correction).