Figure 1.

Sorafenib and doxorubicin treatment inhibits the cellular viability and induces apoptosis of A673 cells in vitro. A673 cells were treated with the indicated concentrations of Sorafenib (left panel) or doxorubicin (right panel) for 48 h. A: Cell viability was assessed by MTT assay. B: Cell cycle distribution assessed by BrdU flow cytometry. C: Apoptotic cell death upon Sorafenib treatment assessed by flow cytometry for Annexin V (AnnV) positivity. The bars represent the mean ± SD of the mean from n=3 individual experiments.