Table 1.

Hemodynamic data at baseline and at 3 months during rest and stress

Variable	Sham	Placebo	Metoprolol	Carvedilol	p value ANOVA
Rest
HR (baseline)	61 ± 8	55 ± 5	54 ± 2	61 ± 7	ns
HR (3 months)	55 ± 7	62 ± 7	54 ± 2	60 ± 5	ns
BP (baseline)	73 ± 5	80 ± 6	81 ± 3	83 ± 6	ns
BP (3 months)	77 ± 4	108 ± 9	84 ± 4*	80 ± 3†	<0.05
DP (Baseline)	52 ± 4	65 ± 7	68 ± 6	72 ± 13	ns
DP (3 months)	60 ± 5	88 ± 12	68 ± 3	85 ± 7‡	0.03
Stress
HR (baseline)	114 ± 5	108 ± 7	119 ± 9	112 ± 9	ns
HR (3 months)	109 ± 10	119 ± 11	109 ± 9	113 ± 10	ns
BP (Baseline)	115 ± 5	114 ± 6	116 ± 7	121 ± 5	ns
BP (3 months)	128 ± 6	175 ± 23	131 ± 7*	138 ± 12	<0.05
DP (Baseline)	201 ± 28	193 ± 14	239 ± 29	208 ± 22	ns
DP (3 months)	227 ± 14	283 ± 34	239 ± 27	251 ± 37	ns

Data are presented as mean ± SEM

HR heart rate, BP mean aortic blood pressure, DP double product/100

^*p<0.05 vs. placebo

^†p<0.01 vs. placebo

^‡p<0.05 vs. metoprolol