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. Author manuscript; available in PMC: 2013 Dec 19.
Published in final edited form as: Kidney Int. 2010 Sep 29;79(1):10.1038/ki.2010.335. doi: 10.1038/ki.2010.335

Figure 3. Genetic-Epigenetic Phenotype.

Figure 3

Each cell has its own epigenetic signature which reflects genotype and environmental influence and is ultimately reflected in the phenotype of the cell and organism. Thus most genetic findings must be considered in an epigenetic and environmental context. The contribution from traditional genetics cannot be unequivocally realized until the complementary epigenetics and environmental changes are considered.