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Toxicity—number of patients.
| Toxicity | Grade 1-2 | Grade 3-4 | Total |
|---|---|---|---|
| Fatigue | 28 (80%) | 2 (5.7%) | 30 (85.7%) |
| Nausea | 24 (68.6%) | 5 (14.3%) | 29 (83%) |
| Vomiting | 16 (45.7%) | 3 (8.6%) | 19 (54.3%) |
| Myelosuppression | 14 (40%) | 2 (5.7%) | 16 (45.7%) |
| Encephalopathy | 6 (17.1%) | 6 (17.1%) | 12 (34.2%) |
| Constipation | 10 (28.6%) | 0 | 10 (28.6%) |
| Diarrhoea | 4 (11.4%) | 2 (5.7%) | 6 (17.1%) |
| Renal function impairment | 5 (14.3%) | 0 | 5 (14.3%) |
| Liver function tests alteration | 1 (2.8%) | 0 | 1 (2.8%) |
