Table 6.
Effect of heat exposure on serum levels of adrenocorticotrophic-hormone (ACTH) and corticosterone in different groups of mice.
Treatment groups | ACTH (pg·mL−1) | Corticosterone (ng·mL−1) |
---|---|---|
(1) Non-heated mice | 392 ± 98 | 142 ± 24 |
(2) Heated mice treated with vehicle solution | 984 ± 127a | 505 ± 26a |
(3) Heated mice treated with melatonin 0.2 mg/kg | 1001 ± 145 | 518 ± 28 |
(4) Heated mice treated with melatonin 1 mg/kg | 1668 ± 162b | 719 ± 31b |
(5) Heated mice treated with melatonin 5 mg/kg | 2167 ± 176b | 854 ± 35b |
Samples were measured 4 hours after whole body heating or the equivalent time period for non-heated groups. aCompared with non-heated group (P < 0.05); bCompared with group 2 (P < 0.05). Data are means ± S.E.M. of 12 mice per group.