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. Author manuscript; available in PMC: 2013 Dec 19.
Published in final edited form as: J Immunol. 2010 Jul 30;185(5):10.4049/jimmunol.1000761. doi: 10.4049/jimmunol.1000761

FIGURE 8.

FIGURE 8

Movement of human resting NK cells over mobile and immobile ICAM-1. NK cells were visualized 20 minutes after injection into chambers containing ICAM-1 bound to either lipid bilayers or glass surfaces, respectively. The movement of NK cells was tracked for 25 frames with a 10 s interval between frames by Dynamic Image Analysis System (DIAS). The cell at the top of the stack is the cell from the last frame. A, Engagement of LFA-1 by diffusible ICAM-1 on lipid bilayer promoted active movement of NK cells. B, Engagement of LFA-1 by solid phase ICAM-1 resulted in arrest and stable binding (left) or spreading and slow movement of NK cells (right).