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. 2013 Oct 2;4(12):1514–1519. doi: 10.1021/cn400036j

Figure 4.

Figure 4

Effect of total amount of pDNA on the transfection efficiency of cationic amino acid based lipid assemblies compared to LA2000. Lipid-to-pDNA ratios of 1 (A) and 3 (B) were used. The concentrations of lipid are (A) 2, 4, 6, and 10 μg/mL at [pDNA] of 0.4, 0.8, 1.2, and 2 μg/mL, and (B) 6, 12, 18, and 30 μg/mL at [pDNA] of 0.4, 0.8, 1.2, and 2 μg/mL, respectively. Data are shown as means ± SEM of eight replicate experiments. Significant dose-dependent increase of the Arg (TFA–) value at a lipid-to-pDNA ratios of 1 were observed in a Kruskal–Wallis test (P < 0.05).