Table 4.
Brain regions showing significant decreases of metabolic activity in RTP and JGG relative to 25 healthy control subjects.
| RTP | JGG | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Region | Side | MNI coordinates | Cluster size | Region | Side | MNI coordinates | Cluster size | ||||||
| x | y | z | z | Vox | x | y | z | z | Vox | ||||
| Precentral gyrus(BA6) | L | −52 | −12 | 31 | 59.39 | Supramarginal gyrus (BA40) | L | −60 | −44 | 27 | 45.22 | ||
| Postcentral gyrus(BA2) | L | −44 | −29 | 40 | 26.22 | Middle temporal gyrus (BA21) | L | −65 | −27 | −9 | 42.99 | ||
| Insula(BA13) | L | −38 | −14 | 21 | 7.82 | 17.32 | Supramarginal gyrus (BA40) | L | −58 | −36 | 41 | 35.85 | |
| Paracentral lobule(BA6) | R | 11 | −29 | 44 | 6.67 | 11.57 | Middle frontal gyrus (BA9) | L | −44 | 16 | 35 | 7.56 | 15.71 |
| Paracentral lobule(BA5) | R | 9 | −42 | 50 | 5.17 | 7.12 | Middle frontal gyrus (BA11) | L | −38 | 38 | −25 | 7.36 | 14.64 |
| Middle occipital gyrus(BA19) | R | 15 | −90 | 9 | 6.44 | 10.74 | Inferior semi-lunar lobule | R | 44 | −71 | −42 | 7.15 | 13.63 |
| Lingual gyrus(BA18) | L | −5 | −84 | −6 | 6.31 | 10.28 | Pyramis | R | 18 | −79 | −28 | 6.90 | 12.50 |
| Middle occipital gyrus(BA18) | L | −14 | −91 | 6 | 6.10 | 9.62 | Cerebellar tonsil | R | 51 | −61 | −34 | 6.86 | 12.34 |
| Middle frontal gyrus(BA10) | L | −29 | 27 | 14 | 5.93 | 9.08 | Middle frontal gyrus (BA6) | L | −33 | 17 | 51 | 6.81 | 12.16 |
| Parahippocampal gyrus(BA19) | L | −29 | −43 | −1 | 5.80 | 8.72 | Cerebellar tonsil | R | −42 | −69 | −41 | 6.25 | 10.10 |
| Lingual gyrus(BA18) | L | −7 | −69 | 4 | 5.67 | 8.36 | Pyramis | R | −18 | −90 | −30 | 5.96 | 9.19 |
| Lingual gyrus(BA19) | R | 17 | −62 | 1 | 5.64 | 8.29 | Pyramis | R | −18 | −81 | −28 | 5.58 | 8.12 |
| Posterior cingulate(BA30) | R | 4 | −65 | 8 | 5.59 | 8.14 | Inferior temporal gyrus (BA20) | L | −51 | −4 | −41 | 6.24 | 10.05 |
| Paracentral lobule(BA5) | L | −11 | −35 | 44 | 5.58 | 8.12 | Inferior occipital gyrus (BA17) | R | 19 | −93 | −4 | 6.15 | 9.77 |
| Caudate (tail) | L | −24 | −31 | 17 | 5.48 | 7.86 | Parahippocampal gyrus (BA35) | R | 20 | −27 | −12 | 5.97 | 9.21 |
| Caudate (tail) | L | −27 | −36 | 12 | 5.42 | 7.72 | Middle occipital gyrus (BA19) | L | −56 | −67 | −1 | 5.94 | 9.13 |
| Precuneus(BA7) | R | 20 | −56 | 43 | 5.45 | 7.79 | Thalamus (pulvinar) | L | −14 | −31 | 1 | 5.86 | 8.90 |
| Middle frontal gyrus(BA10) | L | −32 | 42 | 14 | 5.34 | 7.52 | Thalamus (pulvinar) | L | −22 | −25 | 14 | 5.73 | 8.54 |
| Precuneus(BA7) | R | 4 | −57 | 31 | 5.30 | 7.42 | Precuneus (BA7) | R | 6 | −53 | 51 | 5.75 | 8.57 |
| Declive | R | −7 | −78 | −9 | 5.72 | 8.50 | |||||||
| Lingual gyrus (BA18) | L | −5 | −76 | −3 | 5.28 | 7.38 | |||||||
| Cerebellar tonsil | R | 22 | −48 | −45 | 5.71 | 8.46 | |||||||
| Middle temporal gyrus (BA21) | R | 71 | −11 | −9 | 5.68 | 8.38 | |||||||
| Superior temporal gyrus (BA22) | R | 65 | 1 | −11 | 5.66 | 8.35 | |||||||
| Anterior cingulate (BA24) | L | 1 | 24 | 9 | 5.64 | 8.29 | |||||||
| Declive | R | −20 | −69 | −13 | 5.64 | 8.29 | |||||||
| Declive | R | −27 | −82 | −14 | 5.31 | 7.44 | |||||||
| Inferior temporal gyrus (BA20) | L | −60 | −56 | −10 | 5.57 | 8.11 | |||||||
| Caudate (body) | L | −16 | 2 | 12 | 5.48 | 7.86 | |||||||
| Declive | R | 18 | −67 | −14 | 5.30 | 7.42 | |||||||
| Declive | R | 23 | −56 | −15 | 5.27 | 7.35 | |||||||
FEW p < 0.05 (corrected for multiple comparisons). Localization is based on stereotactic coordinates MNI (Montreal Neurological Institute). These coordinates refer to the location of maximal decrement metabolic activity indicated by the Z score in a particular anatomic structure. Distances are relative, to the intercommissural (AC-PC) line in the horizontal (x), anterior-posterior (y) and vertical (z) directions.