. Author manuscript; available in PMC: 2013 Dec 19.

Published in final edited form as: Arthritis Rheum. 2009 Oct 15;61(10):10.1002/art.24642. doi: 10.1002/art.24642

Table 3.

Univariate random-effects meta-regression assessing potential effects of selected continuous covariates in the observed pooled effect of HLA–B51/B5 on the risk of developing BD^*

Variable	Populations, no.	df	OR (95% CI)	P _cov
BD case characteristics
Male sex, %	44	1	1.02 (1.004–1.03)	0.008
Age at study time, years	20	1	1.00 (0.95–1.06)	0.96
Age at onset/diagnosis, years	5	1	0.95 (0.70–1.29)	0.74
Ocular involvement, %	32	1	1.01 (0.999–1.02)	0.08
CNS involvement, %	16	1	1.02 (0.99–1.05)	0.14
Large-vessel involvement, %	16	1	1.03 (0.99–1.07)	0.10
Year of publication	80	1	0.99 (0.98–1.01)	0.44

The ORs shown in the table can be interpreted as the change in the odds for any one-unit increase of the corresponding covariates. BD = Behçet’s disease; OR = odds ratio; 95% CI = 95% confidence interval; P_cov = P values for significance of covariates in the pooled genetic effect; CNS = central nervous system.