Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) BirA catalyzed biotinylation of ACC, a biotin dependent enzyme. (B) The prototypical bisubstrate inhibitor 5′-O-[N-(biotinyl)sulfamoyl]adenosine is in equibibrium between the anticonformation (5) around the glycosidic linkage and the syn-conformation (6), which can react intramolecularly to liberate N-biotinylsulfamic acid 7 and cycloadenosine 8.
