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. 2013 Dec 6;9(1):87–94. doi: 10.1097/COH.0000000000000027

Table 1.

Changes in World Health Organization recommendations on immunological threshold of when to start antiretroviral therapy by age from 2003 to 2013

Age		<12 months	12–23 months	24–35 months	36–59 months	≥60 months
WHO guidelines
2003 [8]	CD4%	<20%	<15%
	Absolute CD4	NA	NA
2006 [9]	CD4%	<25%	<20%		<15%	<15%
	Absolute CD4	<1500 cells/mm³	<750 cells/mm³		<350 cells/mm³	<200 cells/mm³
2008 [10]	CD4%	All	<20%		<20%	<15%
	Absolute CD4	All	<750 cells/mm³		<350 cells/mm³	<200 cells/mm³
2010 [11]	CD4%	All	All	≤25%		NA
	Absolute CD4	All	All	<750 cells/mm³		≤350 cells/mm³
2013 [7]	CD4%	All	All	All	All	NA
	Absolute CD4	All	All	All	All	≤500 cells/mm³