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Quantitation of mesangial fractional volume (n = 15). A: Representative photomicrographs of PAS-stained glomeruli from kidneys of nondiabetic and diabetic Wt (a,d), GLO1-KD (b,e), and GLO1-Tg (c,f) mice. Original magnification ×600. B: Quantitation of mesangial fractional volume for each group of mice. Data are expressed as mean ± SD (*P < 0.05 vs. Wt; #P < 0.05 vs. STZ-Wt; ANOVA).
