Figure 1.
Cellular localization of GIRK4 in mice heart. Confocal images of GIRK4 KO mice atrial (A) and ventricular (B) tissue sections stained for GIRK4 and Cx43 show that GIRK4 labelling was not detected in GIRK4 KO atrium and ventricle, whereas Cx43 labelling was located in intercalated discs. In contrast to GIRK4 KO mice, confocal images of GIRK1 KO mice atrial (C) and ventricular (D) tissue sections displayed labelling associated with the outer sarcolemma and the ventricular t-tubular system. Scale bar = 10 µm.