Analysis of circulating blood cell composition 24 h following administration of LFs. Mice were given LF (1 mg). The results are presented as the mean value of five mice per group. Statistics: Bands: control versus bLF, P=0.0001; control versus rmLF, P<0.0002; control versus rhLF, P<0.0005; neutrophils: control versus bLF, P<0.005; control versus rmLF, P<0.01; control versus rhLF, NS (P=0.75); eosinophils: control versus bLF, NS (P=0.06); control versus rmLF, P<0.025; control versus rhLF, NS (P=0.3); lymphocytes: control versus bLF, P<0.0002; control versus rmLF, P<0.0005; control versus rhLF, NS (P=0.4); monocytes: control versus bLF, P<0.02; control versus rmLF, NS (P=1.0); control versus rhLF, P<0.0005. B, bands; Ne, neutrophils; E, eosinophils; L, lymphocytes; M, monocytes; NS, not significant; LF, lactoferrin; rmLF, recombinant mouse LF; rhLF, human recombinant lactoferrin; bLF, bovine milk-derived LF.