Table 5. Comparison of voltage-dependence of activation and inactivation parameters between Nav1.5 conjugated or not with GFP.
| Nav1.5 construct |
Activation
|
Inactivation
|
|||||
|---|---|---|---|---|---|---|---|
| Vh (mV) | k (mV) | Time to peak (ms) | Vh (mV) | k (mV) | τf (ms) | τs (ms) | |
| WT | -38.8±2.6 | 6.1±0.9 | 0.5±0.2 | -81.7±6.0 | 6.1±0.4 | 0.9±0.2 | 6.3±0.7 |
| WT-GFP | -38.5±2.4 | 6.4±0.7 | 0.4±0.2 | -79.2±5.5 | 7.1±0.8 | 1.1±0.8 | 6.2±2.0 |
Vh and k, midpoint and slope of the activation and inactivation curves. τf and τs, fast and slow time constants of inactivation. Values are the mean±SEM of 10 experiments in each group.