Figure 1.

Lower levels of expression of SCN2A and Cu-Zn superoxide dismutase (SOD) in patients with secondary epilepsy. (A) Significantly lower expression levels of SCN2A mRNA in patients with primary and secondary epilepsy was observed by quantitative polymerase chain reaction. Different characters showed significant difference among the groups (P<0.05). (B) Lower protein expression in patients with secondary epilepsy by western blotting. (C) Significant signals were observed in normal tissues compared with the cerebral cortexes of patients with primary and secondary temporal lobe epilepsy by immunohistochemistry. (D) Cu-Zn SOD concentration among the normal cortex tissues, the cerebral coretex tissues of patients with primary temporal lobe epilepsy and those with secondary temporal lobe epilepsy. Different letters (a or b) show significant differences among the groups (P<0.05).