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. 2013 Dec 19;8(12):e82683. doi: 10.1371/journal.pone.0082683

Figure 2. Prevention of platelet aggregation by Aspirin reverses thrombocytopenia and reduces LPS-induced lung inflammation in F508del mice.

Figure 2

A. Pretreatment with Aspirin increased blood platelet counts; B. Pretreatment with Aspirin reduced plasma TXB2 levels in LPS-challenged F508del mice compared to LPS-challenged F508del mice receiving vehicle; C–D. Administration of aspirin reduced BAL neutrophils and protein levels in LPS-challenged F508del mice compared to LPS-challenged F508del mice receiving vehicle. N = 5 in each group. Data were analyzed by t-test and presented in mean ± SD. P values are listed on each panel.